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13. Allessie MA, Bonke FIM, Schopman FJG: Circus movement in rabbit atrial muscle as a mechanism of tachycardia: III. The "leading circle" concept: A new model of circus movement in cardiac tissue without the involvement of an anatomic obstacle. Circ Res 1977; 41: 9-18 Dillon SM, Allessie MA, Ursell PC, Wit AL: Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts. Circ Res 1988; 63: 182-206 Wit AL, Dillon SM: Anisotropic reentry, in Zipes DP, Jalife J eds ; : Cardiac Electrophysiology: From Cell to Bedside. Philadelphia, WB Saunders Co, 1990, pp 353-364 16. Allessie MA, Schalij MJ, Huybers MSP, Boersma LVA: Ventricular anisotropy causes an excitable gap in reentry without an anatomic obstacle abstract ; . Circulation 1988; 78: 612 Friedman PL, Stewart JR, Fenoglio JJ, Wit AL: Survival of subendocardial Purkinje fibers after extensive myocardial infarction in dogs. Circ Res 1973; 33: 597-611 Brugada P, Waldecker B, Kersschot I, Zehender M, Wellens HJJ: Ventricular arrhythmias initiated in four groups of patients with myocardial infarction. JAm Coll Cardiol 1986; 8: 1035-1041.
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Jects. We hypothesized that a synchronous decline in GFR in pairs of stable kidney transplant recipients by temporarily increasing cyclospormne doses indicates intrinsic organ or donor ; factors, whereas a differential ent ; modulation factors. in GFR indicates extrinsic or recipi and guanethidine.
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Sections were then dehydrated through increasing graded series of ethylic alcohol and embedded in one block of paraffin wax. Serial slices 3 m ; were cut and stained with 1 ; hematoxylin and eosin to assess the general morphology; 2 ; May-Grunwald Giemsa modified for paraffin sections to enable the quantification of eosinophils; 3 ; Verhoeff Van Gieson's method for the demonstration of elastic fibers measurement of vessel wall areas and 4 ; immunohistochemical IHC ; staining with monoclonal antibody anti-smooth muscle actin 47 ; counting of the number of blood vessels ; . Eosinophils were counted around perivascular and peribronchial areas of each section superior, median, and caudal ; of the left lobe with a light microscope Axioscop; Carl Zeiss, Feldbach, Germany ; at 400 magnification using a 0.060-mm2 calibrated grid. Approximately 20 grids were counted per section. For each animal, the mean numbers of peribronchial and perivascular eosinophils were calculated for the three sections. Morphometric analyses were performed using the image analysis software Image Access 3.2 IMAGIC, Glattbrugg, Switzerland ; . The stained slides were examined with a light microscope DMR BE; Leica Microsystems, Glattbrugg, Switzerland ; connected to a video digitizing camera Prog Res 3008; Jenoptic LOS, Eching, Germany ; . Fifteen pictures from the left lobe 5 of each part, i.e., superior, median, and caudal, respectively ; were captured at 50-fold magnification on Verhoeff-stained slides. Approximately 60 arteries diameters between 30 and 300 m ; were measured per lung. The areas of the external lamina elastica EEL ; and of the internal lamina elastica IEL ; were manually circumscribed. For each artery, the difference between the area of the EEL and IEL was calculated. A mean wall artery area was obtained for each animal. Fifteen pictures from the left lobe 5 of each part, i.e., superior, median, and inferior, respectively ; were captured at 100-fold magnification on IHC anti-smooth muscle actin-stained slides. Smooth muscle actin was demonstrated by IHC staining with monoclonal and guanfacine.
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Anaemia of end-stage renal disease can be managed relatively successfully by recombinant human erythropoietin EPO ; . Iron administration plays a central role in enhancing anaemia responsiveness to EPO. Serum ferritin concentration and iron saturation ratio are among the two most commonly used markers of iron status in maintenance dialysis patients [1]. According to National Kidney Foundation NKF ; Kidney Disease and Dialysis Outcome Quality Initiative K DOQI ; guidelines, iron administration should be withheld for a serum ferritin level 800 ng ml in these patients, since such high ferritin levels may reflect iron overload [2]. However, serum ferritin is also an acute phase reactant and can be increased in inflammation [35]. Inflammation is quite common in maintenance dialysis patients, and its prevalence among maintenance haemodialysis MHD ; patients may be as high as 4060% [6]. Hence, it is quite possible that high levels of serum ferritin are engendered by inflammation independently of iron stores. However, it is not clear whether serum ferritin is indeed significantly increased in inflammation at different levels of body iron in dialysis patients. Moreover, inflammation is closely related to.
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ACCREDITATION STATEMENT This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education ACCME ; through the joint sponsorship of The University of Cincinnati College of Medicine and IMED Communications. The University of Cincinnati College of Medicine is accredited by the ACCME to provide continuing medical education CME ; for physicians. DESIGNATION OF CREDIT The University of Cincinnati College of Medicine designates this educational activity for a maximum of 1.5 AMA PRA Category 1 Credit s ; TM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Release Date: May 31, 2006 Expiration Date: No credit will be given after May 31, 2007.
I thank L. Baggio and B. Yusta for suggestions and critical review of the manuscript. Received September 2, 2003. Accepted September 3, 2003. Address all correspondence and requests for reprints to: Dr. D. J. Drucker, Toronto General Hospital, Banting and Best Diabetes Centre, 200 Elizabeth Street, MBRW4R-402, Toronto, Ontario, Canada M5G 2C4. E-mail: d.drucker utoronto . Work in the author's lab was supported in part by operating grants from the Juvenile Diabetes Research Foundation, the Canadian Diabetes Association and the Canadian Institutes for Health Research. He is a consultant to Amylin Pharmaceuticals Inc., Eli Lilly Inc., Conjuchem Inc., Aventis Inc., Merck Research Laboratories, Novartis Inc., and Bristol Myers Squibb Inc and halcion.
Table 20.1 Causes of renal disease and electrolyte disturbances in persons with HIV infection.
Julie Meashey, MAG, serves as the Ombudsman Specialist for the National Long-Term Care Ombudsman Resource Center and provides technical assistance and support to the 53 state and 600 + local ombudsman programs who serve over 2 million residents in nursing homes, assisted living, and other board and care facilities. She coordinates annual training for State Ombudsmen and has expertise in the areas of volunteer management, mental health, and residents' rights. Before joining the Center staff, Ms. Meashey served as a regional ombudsman in North Carolina serving 5 counties in the western part of the state and halofantrine.
Table 2. Immunodeficiency Cancer Registry ICR ; cases: incidence of tumors and immunodeficiencies.64 Median Age Diagnosis yr. ; 1.6 1.2 23.0.
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Stranding events provide a tremendous amount of information to researchers and resource managers. The information collected provides many insights into the lives of whales and dolphins including seasonal distribution, natural history, population health, environmental contaminant levels, cases of human interaction, and incidence of disease. In some cases, the only existing information about certain species has been learned from stranding events. For example, pygmy sperm whales strand commonly but are seldom observed in the wild, and much of our knowledge of this species has come from stranded animals. Potential disease and environment threats to wild populations were not well studied until hundreds of bottlenose dolphins stranded in the late 1980's due to a morbillivirus outbreak off the east coast of the United States. Other anthropogenic impacts e.g., sonar and acoustic pollution ; have been implicated with recent beaked whale strandings 210.
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